Earn to Die 3 starts by showing a short earn to die 2 movie trailer, where a message is sent to all the survivors to reach the evacuation point (a military base) to be carried to the safe place. The player reads the message and pinpoints the evacuation point in his map. The game starts and the player finds himself in riding a red firefighting truck.
By using the up arrow key on the keyboard the players accelerate the truck and reaches a few miles down killing the zombies on the way and smashing the boxes before the fuel runs out. At the end of this first stage, the player gathers enough money to buy extra fuel in order to reach closer to the destination point. By leaps and bounds, the player gathers enough money to upgrade his/her vehicle, buy more powerful ammunition and change the tires and other body parts of the truck.
Earn to Die 3 is different than the earlier two versions of the game in the sense that it requires more driving skills, more powerful guns, and more powerful vehicles to reach the evacuation point. The players face greater and harder obstructions, more powerful Zombies and more challenges in Earn to Die 3.